DOI: https://doi.org/10.36347/sjmcr.2026.v14i03.032

Pages: 457-458

Background: Cigarette smoking is a major global health concern and a recognized risk factor for chronic kidney disease. Structural renal alterations may occur before the onset of measurable functional impairment and can be detected using ultrasound. Objective: This study aimed to assess the impact of cigarette smoking on renal morphology using ultrasound and to correlate imaging findings with renal function parameters. Methods: A prospective cross-sectional study was conducted on 150 adult participants, including 60 smokers and 90 non-smokers. Renal ultrasound examinations were performed to measure kidney length, width, parenchymal thickness, and echogenicity. Serum creatinine levels and glomerular filtration rate (GFR) were evaluated. Statistical analysis was performed using SPSS, and significance was set at p < 0.05. Results: Smokers demonstrated significantly reduced renal length and parenchymal thickness compared with non-smokers. Renal echogenicity grades were significantly higher among smokers. Additionally, smokers showed higher serum creatinine levels and lower GFR values. Increasing pack-years of smoking was associated with progressive deterioration of renal ultrasound parameters. Conclusion: Cigarette smoking has a significant adverse effect on renal morphology and function. Renal ultrasound is a valuable, non-invasive modality for early detection of smoking-related renal changes.