DOI: https://doi.org/10.36347/sjmcr.2026.v14i04.005

Pages: 611-614

Giant condyloma acuminatum (GCA), or Buschke–Löwenstein tumor (BLT), is a rare HPV-associated verrucous lesion that exhibits locally aggressive behavior despite often having a benign histology. We report the case of a 46-year-old patient with no significant past medical history, presenting with a large verrucous lesion that had been evolving for 10 years, extending from the scrotum to the posterior perineum and into the perianal region. Rectocolonoscopy revealed no abnormalities. Pelvic MRI showed a nodular parietal thickening involving the scrotum, inguinal regions, and perianal region, measuring approximately 60 × 170 mm. Complete multidisciplinary surgical excision was performed in collaboration with the colorectal surgeons, combined with a protective colostomy, followed by secondary closure surgery. The outcome was favorable with no recurrence at follow-up.