DOI: https://doi.org/10.36347/sjmcr.2026.v14i04.013

Pages: 647-650

Amniotic membrane transplantation (AMT) has demonstrated significant efficacy in the management of various ocular surface disorders due to its unique biological properties. These include anti-inflammatory, anti-fibrotic, and anti-angiogenic effects, as well as its ability to promote epithelial cell migration and enhance corneal healing. The aim of this study was to evaluate the effectiveness of amniotic membrane transplantation in the treatment of different ocular surface pathologies. We conducted a prospective study including all patients treated with amniotic membrane transplantation for ocular surface diseases between September 2023 and September 2025. All patients were followed for a minimum period of six months. Demographic data, clinical indications, surgical characteristics, and postoperative outcomes were analyzed. A total of 27 patients underwent amniotic membrane transplantation. The mean age of the patients was 42.7 years, with a slight male predominance (52.5%). Indications for surgery included corneal ulcers (7 patients), corneal perforations (2 patients), ocular burns (3 patients), infectious keratitis (15 patients), orbital implant exposure (1 patient), and severe dry eye syndrome (1 patient). Baseline visual acuity was ≤1.3 LogMAR in 85.6% of cases. Most procedures were performed under local anesthesia (85.18%). Postoperatively, the mean visual acuity improved to 1 LogMAR, with an average gain of three lines. Suture dehiscence occurred in two patients. The most frequent postoperative finding was corneal neovascularization, observed in 74.07% of cases. Amniotic membrane transplantation is widely used in the treatment of ocular surface diseases due to its multiple therapeutic properties, including facilitation of epithelial cell migration, enhancement of basal cell adhesion, promotion of epithelial differentiation, modulation of stromal healing, and anti-inflammatory and antibacterial effects. AMT represents a simple and effective surgical technique th