DOI: https://doi.org/10.36347/sjmcr.2026.v14i04.023

Pages: 680-683

Enhancement observed after the injection of gadolinium chelates in brain magnetic resonance imaging (MRI) constitutes a fundamental pillar of neuroradiological diagnosis [1, 2]. This phenomenon, a consequence of a breach in the blood-brain barrier (BBB) or pathological angiogenesis, enables the detection, precise delineation, and phenotypic characterization of a wide spectrum of intracranial pathologies (tumors, abscesses, inflammatory processes, vascular lesions) [3]. The systematic analysis of the morphology (ring-like, nodular, homogeneous, gyriform), intensity, kinetics, and topography of the enhancement, performed at an optimal post-injection delay, is essential for guiding differential diagnosis. It is imperative to recall that a lesion that does not exhibit contrast enhancement can nevertheless be pathological, as is the case for certain low-grade gliomas or very early ischemic lesions [4]. This review aims to detail the various semiological aspects of enhancement and their pathophysiological correlates, in order to provide young radiologists with a reasoned framework for image interpretation in clinical practice.