DOI: https://doi.org/10.36347/sjmcr.2026.v14i04.024

Pages: 684-688

We report an exceptional case of association between Sturge-Weber syndrome, Dyke-Davidoff-Mason syndrome, and developmental venous anomalies in a 24-year-old patient admitted to the emergency department for generalized epileptic seizures, associated with a left fronto-orbital port-wine stain, cognitive impairment, facial asymmetry, and ipsilateral glaucoma. Multimodal imaging (CT and MRI) revealed gyriform cortical calcifications, cerebral hemiatrophy with compensatory hyperostosis, as well as intraparenchymal venous anomalies consistent with impaired venous drainage. Management with antiepileptic therapy and ocular hypotensive agents resulted in satisfactory seizure control and improved quality of life. This rare association suggests shared pathophysiological mechanisms and highlights the major role of imaging in diagnosing these complex neurovascular interactions.