DOI: https://doi.org/10.36347/sjmcr.2026.v14i04.064

Pages: 856-864

Background: Cervicofacial actinomycosis (CFA) is a rare but treatable infection typically associated with poor dental hygiene, immunosuppression, or prior mucosal injury in the upper aerodigestive tract. Although rare, when cervicofacial actinomycosis involves the larynx, it may be misinterpreted as a mucosal mass. Moreover, reports of association with laryngeal carcinoma are exceptionally rare in the literature. Case presentation: A male patient, in his fifth decade, presented with laryngeal carcinoma accompanied by actinomycosis, which was confirmed through biopsy. The patient received antibiotics to treat the infection and was subsequently referred for radiotherapy, as he declined surgical intervention for his carcinoma. His condition showed a favorable clinical outcome during follow-up. Conclusion: The simultaneous occurrence of laryngeal carcinoma and actinomycosis is exceedingly rare, making it a particularly unusual clinical scenario. Clinicians should be vigilant in evaluating patients with laryngeal carcinoma for signs of actinomycosis, as timely recognition and appropriate management of this rare co-occurrence can significantly impact patient outcomes and prevent misdiagnosis or delayed treatment.