DOI: https://doi.org/10.36347/sasjs.2026.v12i05.004

Pages: 354-359

Background: Central giant cell granuloma (CGCG) is a benign intraosseous lesion of the jaws that commonly presents in children and young adults. It is classified into aggressive and non-aggressive subtypes. Aggressive lesions are relatively rare but may show rapid progression and cause significant morbidity due to bone destruction and displacement of teeth. Case Presentation: We report a case of a 7-year-old girl who presented with swelling on the right side of the lower jaw for one month, associated with gradual increase in size and loosening of teeth. Diagnosis of central giant cell granuloma was established using imaging and histopathological examination. The patient initially underwent incisional biopsy, followed by denosumab injections. Subsequently, she underwent wide local excision of the mandibular lesion with reconstruction using a free fibula flap. Conclusion This case highlights the importance of considering central giant cell granuloma in the differential diagnosis of rapidly progressive mandibular lesions in the paediatric age group. Early diagnosis and multidisciplinary management can significantly improve long-term functional and cosmetic outcomes.