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Scholars Journal of Medical Case Reports | Volume-14 | Issue-05
Jaundice Revealing Multiple Primary Neoplasia and Krukenberg Tumour: A Case Report
Sara Hdiye, Firdaouss Ait Iken, Chaimae Hdiye, Rachid Laroussi, Sanaa Berrag, Fouad Nejjari, Tarik Adioui, Mouna Tamzaourte
Published: May 14, 2026 |
14
9
Pages: 994-998
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Abstract
Krukenberg tumours are ovarian malignancies secondary to signet-ring cell adenocarcinomas. Gastric and colorectal cancers account for almost 90% of primary sites. Other less frequent primary sites are described in the literature. We report the case of a Krukenberg tumour discovered incidentally during the investigation of jaundice. This 55-year-old patient was referred to the emergency department for investigation of cutaneous jaundice associated with chronic epigastralgia resistant to symptomatic treatment. The initial radiological work-up showed dilatation of the bile ducts associated with the presence of 2 ovarian masses. Additional magnetic resonance cholangiography revealed a lesional process of the biliary bifurcation related to a cholangiocarcinoma, and the esophagogastroduodenoscopy performed as part of the exploration of chronic epigastralgia revealed a gastric tumour. The overall clinical picture suggested a multiple primary tumor syndrome with perihilar cholangiocarcinoma and gastric adenocarcinoma complicated by Krukenberg tumors. The patient underwent palliative biliary drainage with a transhepatic percutaneous prosthesis and died a few days later. Krukenberg's tumour is rare, and its prognosis is poor, especially when it occurs in the setting of multiple primary neoplasia. The aim of our work is to shed light on the rarity of this disease and its insidious evolution, responsible for erratic and delayed diagnosis.


