DOI: https://doi.org/10.36347/sjmcr.2026.v14i05.103

Pages: 1298-1301

Fibrodysplasia ossificans progressiva (FOP) is a rare and disabling genetic disorder characterized by progressive heterotopic ossification of soft tissues and congenital skeletal malformations, particularly of the great toes. We report the case of a 13-year-old girl with no significant past medical history, presenting with progressive, painless stiffness of the spine and limbs, more pronounced at the elbows. The condition evolved through inflammatory flare-ups in an atraumatic and afebrile context, with preserved general condition. Clinical examination revealed cervical spine straightening, bilateral elbow tendon retractions, and bilateral hallux valgus deformity. Radiographic evaluation demonstrated soft tissue calcifications in the right thigh, bilateral monophalangic great toes with hallux valgus, bilateral periarticular heterotopic ossifications at the distal humerus, and extensive spinal heterotopic ossifications with posterior arch fusion from C3 to C6 on CT scan. Early recognition of the characteristic clinical and radiologic features of FOP is crucial to avoid unnecessary invasive procedures that may exacerbate disease progression.