An International Publisher for Academic and Scientific Journals
Author Login
Scholars Journal of Applied Medical Sciences | Volume-14 | Issue-06
Role of Neutrophil-Lymphocyte Ratio in the Differentiation Between Simple and Complex Febrile Seizure in Children
Papia Sultana, Md Zakirul Islam, Md Arifuzzaman, Fatema Tuz Jahura, Mehnaz Tabassum, Marium Alam Noor, Asif Iqbal, Musammat Fatima Tuz Zahura, Hemamalini Roy
Published: June 2, 2026 |
7
8
Pages: 894-898
Downloads
Abstract
Background: Febrile seizures (FS) are categorized into simple febrile seizures (SFS) and complex febrile seizures (CFS). Differentiating between these types is clinically important due to the higher risk of complications associated with CFS. The neutrophil-lymphocyte ratio (NLR), an inflammatory marker, may aid in this distinction. Aim: To evaluate the role of neutrophil-lymphocyte ratio in differentiating between simple and complex febrile seizures in children. Methods: This cross-sectional analytical study was conducted from March 2023 to February 2024 at the Department of Paediatrics, Sir Salimullah Medical College Mitford Hospital. A total of 114 children were enrolled, including 57 with SFS and 57 with CFS, selected by purposive sampling. Clinical and laboratory data were recorded, and blood samples were collected within 20 minutes of hospital arrival. Statistical analysis was performed using SPSS version 26. Results: The mean NLR was significantly higher in children with CFS compared to those with SFS (p=0.00011), indicating a strong association between elevated NLR and complex febrile seizures. Conclusion: Neutrophil-lymphocyte ratio is a useful and readily available biomarker for differentiating between simple and complex febrile seizures in children.