DOI: https://doi.org/10.36347/sjmcr.2026.v14i06.017

Pages: 1395-1396

Gaucher disease (GD) is a lysosomal storage disorder that frequently results in severe skeletal morbidity [1,2]. While marrow infiltration is the primary event, the secondary structural complications—specifically vertebral collapse and osteonecrosis—are best characterized by computed tomography (CT) [1]. We report the case of a 25-year-old male with long-standing GD presenting with classic "H-shaped" vertebrae and bilateral femoral head involvement. This report highlights the CT semiology of Gaucher-related bone disease, focusing on the biconcave vertebral deformity resulting from central endplate ischemia and the progression of aseptic osteonecrosis.