DOI: https://doi.org/10.36347/sjmcr.2026.v14i06.018

Pages: 1397-1399

Rhabdomyosarcoma is the most common soft tissue sarcoma in children and frequently involves the head and neck region. Parameningeal locations are associated with delayed diagnosis and poor prognosis due to their deep anatomical position and proximity to critical neurovascular structures. We report the case of a 12-year-old girl presenting with rapidly progressive craniofacial symptoms. Imaging revealed an aggressive skull-base mass with extensive sinonasal, orbital, and intracranial involvement. Histopathological analysis confirmed alveolar rhabdomyosarcoma. Despite initial response to chemotherapy, the disease progressed with leptomeningeal dissemination. This case highlights the essential role of imaging in early diagnosis, staging, and prognostic assessment.