DOI: https://doi.org/10.36347/sjams.2026.v14i06.018

Pages: 980-985

Background: Chronic kidney disease (CKD) in children is frequently accompanied by anemia and a progressive decline in glomerular filtration rate (GFR), both of which contribute to disease burden and poor outcomes. Nutritional interventions, particularly protein intake aligned with recommended daily allowance (RDA), may influence renal function and hematological status. This study aimed to evaluate the association between hemoglobin (Hb) and GFR in children with CKD following RDA-based protein intervention. Methods: This clinical trial was conducted at Dhaka Shishu Hospital from January 2016 to December 2017. Thirty children aged 2–18 years with CKD stages II–V (non-dialysis) were included. Participants received RDA-level protein intake according to WHO guidelines and were followed for six months. Hb and GFR were measured at baseline and after intervention by protein RDA at 3 months and 6 months. Statistical analysis was performed using paired t-tests and Pearson correlation in SPSS version 22, with significance set at p ≤ 0.05. Results: Among 30 patients, the mean age was 8.10± 3.7 years, with a male predominance (70%). The majority (53.3%) were in the 6 to 10 years age group. At baseline, 53.3% had mild anemia, 33.3% moderate and 13.3% severe anemia. Mean Hb increased significantly from 9.44± 2.08 g/dL at baseline to 10.98 ± 1.33 g/dL at six months (p less than 0.001).