DOI: https://doi.org/10.36347/sjams.2026.v14i06.020

Pages: 994-1000

Perinatal stroke is defined as a cerebrovascular event that occurs between the 20th week of gestation and 28 days after birth. Perinatal stroke is one of the leading causes of neurological morbidity in newborn infants. The presentation of stroke in newborn infants can range from symptomatic seizures to completely asymptomatic that are only diagnosed with stroke through neuroimaging studies. The presentation of stroke in newborn infants can be challenging to recognize due to the non-specificity of the signs and symptoms. Herein we reported two newborn infants who were diagnosed with perinatal stroke. The first is a full-term female who developed seizures at the third day of life with an infarction in the territory of the left middle cerebral artery with hemorrhagic transformation. While the second case is a male neonate who developed respiratory distress after delivery; stroke was incidentally found on cranial ultrasonography, subsequently cortical infarction with cerebral sinovenous thrombosis confirmed by CT scan, followed by MRI studies.