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Scholars Journal of Applied Medical Sciences | Volume-14 | Issue-07
Hypertension in Women with Obesity: A Systematic Narrative Review of Pathophysiology, Clinical Impact, and Evidence-Based Management
Hanan AL Shammari, Neelufur Sulaiman Sait
Published: July 11, 2026 | 21 13
Pages: 1043-1047
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Abstract
Background: Obesity and hypertension commonly occur together in women and significantly increase the risk of cardiovascular disease. Hormonal factors such as pregnancy and menopause further influence this risk. Objective: To review the causes, clinical impact, and management of hypertension in women with obesity. Methods: A narrative review of studies published between 2000 and 2025 was conducted using PubMed and other major databases, focusing on female-specific data. Results: Obesity increases blood pressure through mechanisms such as sympathetic nervous system activation, renin–angiotensin system stimulation, inflammation, and insulin resistance. In women, reduced estrogen levels after menopause worsen vascular function. Conditions like polycystic ovary syndrome and preeclampsia further increase risk. This combination leads to higher rates of heart disease, stroke, and kidney disease. Conclusion: Early screening and management using lifestyle changes and medications are essential. A women-specific approach can improve outcomes and reduce long-term complications.