DOI: https://doi.org/10.36347/sasjm.2026.v12i09.011

Pages: 905-907

Introduction: Buschke-Lowenstein tumor (BLT) is a sexually transmitted disease caused by human papillomavirus (HPV), described as an intermediate form between condyloma acuminata and squamous cell carcinoma. It mainly affects the genital and anorectal areas; Extragenital condyloma acuminatum not associated with sexual activity is rare and clinicians should inquire about a patient's medical condition and immune status. Clinical case: We present the case of 57-year-old patient, with a history of unprotected sex with multiple partners, and type 2 diabetes who consults for multiple warty lesions which began on the scrotum and has progressed for 15 years to invade the inguinal and suprapubic region and finally the right axillary vault. Treatment consisted in a complete surgical resection of the tumor with no recurrence during a 5-year follow-up period. Conclusion: BLT is locally aggressive and challenging to treat, so prevention against HPV is essential.