DOI: https://doi.org/10.36347/sasjs.2026.v12i09.008

Pages: 782-786

Background: Infections of wounds have long been recognized as a leading source of illness, especially in trauma patients, but are becoming further complicated due to antimicrobial resistance. Knowing the microbial flora and its sensitivity to antibiotics is important to guide empirical treatment. Methods: This hospital-based cross-sectional study was done in the Trauma Management Centre, under the Surgery Department, Combined Military Hospital, Dhaka from August 2024 to January 2025. Total 100 patients who had wound infections were included in the study through a convenience sampling technique. Following asceptic precaution the pus samples were collected, used for culture and identification of the causative bacteria. Sensitivity testing of antibiotic was done through Kirby–Bauer disc diffusion technique. Results: All the subjects were males with an average age of 26.28 ± 8.58 years. Gram negative bacteria were prevalent (80%), among which Acinetobacter spp. and Klebsiella spp. were the most common (22% each), followed by Pseudomonas spp. (16%). S. aureus constituted 20%. Colistin showed maximum sensitivity (68%), followed by imipenem (36%), whereas, ciprofloxacin (26%), ceftriaxone (24%) and amikacin (24%) showed low sensitivity. Colistin was 100% sensitive to Pseudomonas spp. and Acinetobacter spp. Ceftriaxone (76%) and ciprofloxacin (74%). shown high resistance rates. Conclusion: Gram-negative bacteria, especially Acinetobacter and Klebsiella species, prevailed and showed high resistance to various antibiotics. The two most effective drugs, colistin and imipenem, underscored the need for judicious use of antibiotics and therapeutic cultures.