DOI: 10.36347/sjet.2020.v08i08.003

Pages: 155-161

The antioxidant property of the methanol and ethanol extracts from various parts of Clerodendrum infortunatum L. was examined in vitro. Antioxidant activity was evaluated by using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) assay. The free radical scavenging activity of ethyl acetate fraction was superior to all other fractions (IC50 = 16.45 μg/ml), which was higher than synthetic antioxidant butylate dhydroxy anisole, BHA, (18.27 μg/ml). Furthermore, the amount of total phenolic compounds was determined and its content in EtOAc fraction (12.25%) was the highest as compared to other extract or fractions. The essential oil and organic extracts also showed potent antibacterial activities against the tested bacteria such as Escherichia coli ATCC 35218, Methicillin-resistant Staphylococcus aureus (isolate), Klebsiella pneumoniae ATCC 700603, Pseudomonas aeruginosa ATCC 27853 and Enterococcus faecalis ATCC 291212. Our study suggests that natural products derived from Clerodendrumin fortunatum L. have the potential to be used as food preservatives.