DOI: 10.36347/sajb.2020.v08i02.005

Pages: 46-50

Introduction: Sexually Transmitted Infections (STIs) remains a public health problem due to their high number in the world, the asymptomatic nature of several cases and the consequences on the fertility of untreated affected people. The objective was to assess the performance of the newly acquired Anyplex TM STI-7 Detection (V1.1) technique compared to that used in routine Abbott Real Time m2000 in the detection of Chlamydia trachomatis and Neisseria gonorrhoeae. Materiel and Methods: Retrospective study on a population of 283 people who could potentially have an STI. All urine samples are run on both methods. AnyplexTM STI7 Detection (V1.1) capable of detecting 7 pathogens including Chlamydia trachomatis and Nesseria gonorrhoeae compared to the routine one that we will consider as the reference one: Abbott Real Time m2000 CT/ NG. Results: For Chlamydia trachomatis, the sensitivity is 100% [50.01, 100], the specificity of 97.5% [95.39, 99.01], the positive predictive value of 40% [16.82, 68.73], the negative predictive value of 100% [98.61, 100] and Cohen's Kappa of 0.56 [0.45, 0.66] and for Neisseria gonorrheae, the sensitivity amounts to 33.33% [6.14, 79.23], the specificity to 99.28 % [97.43, 99.80], the positive predictive value at 33.33% [6.14, 79.23], the negative predictive value at 99.28% [97.43, 99.80] and Cohen's Kappa at 0.33 [0.20, 0.44]. Conclusion : Our results showed a good sensitivity for Chlamydiae trachomatis allowing a use of this test in first intention. An assessment on a larger number of positive samples to confirm or deny this trend.