DOI: 10.36347/sajb.2020.v08i05.003

Pages: 127-132

Antimicrobial resistance is one of the most pressing issues of modern epoch, according to WHO’s reports of recent decades. In current paper, 6 new synthetic derivatives of natural antimicrobial compound from plant source – L-tartaric acid, were elaborated in National Polytechnic University of Armenia (NPUA). Biological activity and biodegradation potential of benzyl- cyclohexyl- and phenyl- imides and complex mono amino salts of tartaric acid were tested on phytopathogenic Pseudomonas syringae of soil. Due to results, benzyl- and cyclohexyl- complex salts of tartaric acid are more effective then phenyl mono amino salt. As the prospective and a comparably ecologically safe alternative for combating antimicrobial resistance in this plant pathogen P. syringae, complex salts are more effective than the appropriate imide derivatives. The obtained compounds are effective against the other opportunistic pathogenic Pseudomonas (P. aeruginosa, P. fluorescens, etc.). Besides, they are biodegradable by soil non-pathogenic P. chlororaphis group representatives.