DOI: 10.36347/sajb.2020.v08i06.004

Pages: 161-164

Objective of this research work is to determine the spectrum of chronic kidney disease, for patients followed up in the Rajendra Institute of Medical Sciences, Ranchi. A registry analysis of all children with chronic kidney disease followed in dept. of paediatrics during the year 2017 was conducted. Demographic data such as sex, height, and date of birth, as well as the serum BUN, creatinine, diagnosis and the duration of chronic kidney disease at the time of follow up were all recorded. Chronic kidney disease was calculated from serum creatinine based on Schwartz formula. CKD was divided to 4 stages according to the Kidney Disease Outcomes Quality Initiatives guidelines, for stratification of chronic kidney disease. A total number of 117 patients, 64 (54.7%) males, and 53 (45.3%) females were included in the study. Statistical Package for Social Studies version 10 was used to analyze the data. The mean age was 8.6 ± 4.7 years, and the mean duration of follow up was 6.7± 2.3 years. The mean glomerular filtration rate for the whole study population at the time of recording was 28.6 ± 19.58 ml/min/1.73m2. The most common cause of chronic kidney disease was Glomerulopathy (30.8%) of total, followed by Reflux nephropathy (17.1%). Reflux Nephropathy, and Obstructive Uropathy were more common in males when compared to females; whereas Neurogenic Bladder and Hemolytic Uremic Syndrome were more common in females. The most common cause of chronic kidney disease in patients with end stage renal disease at the Rajendra Institute of Medical Sciences, Ranchi was glomerulonephritis (19.4%), followed by oxalosis (16.1%). The spectrum of chronic kidney disease in Jharkhand is similar to other places with some peculiar features that need further study including the high prevalence of neurogenic bladder and oxalosis.