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SAS Journal of Medicine | Volume-6 | Issue-12
Microcytosis: Etiological Discussion about 280 Cases
Khayati S, Bahri R, El Farssani F, Yahyaoui H, Ait Ameur M, Chakour M
Published: Dec. 3, 2020 | 137 99
DOI: 10.36347/sasjm.2020.v06i12.001
Pages: 232-234
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Abstract
Introduction: Anemia is defined by: a decrease in hemoglobin (Hb) level based on normal values for age. We talk about microcytosis for an average globular volume (MCV); whose reference value is between 80 and 100 fl in adults; less than 80 fl. Material and method: We conducted a prospective study over a period of two months in the hematology laboratory of the Avicenne hospital in Marrakech. Complete blood counts (CBCs) were performed on samples. A blood smear, stained with the May-Gründwald-Giemsa stain, was performed for all patients. Were included in our study, all CBCs including MCV <80 fL in adults and <71 fL in children. Results: During the study period, 3682 NFS were performed. 280 microcytoses were detected. The average VGM was 73.8 fl. In the blood smear, the most common blood cell abnormalities were anisopoikilocytosis (97%), microcytosis (90%) and hypochromia (85%). Exploration of these microcytoses revealed a predominance of iron deficiency, found in 48% of cases, 21% of pseudopolyglobulie, 18% of inflammation, 3% of hemoglobinopathy, and in 10% of cases, no etiology was found. Conclusion: This study confirmed the value of a complementary assessment when detecting microcytosis. In particular, it can detect iron deficiencies and hemoglobin abnormalities. In the event of a difficult etiological diagnosis, cooperation between clinician and biologist is essential.