DOI: 10.36347/sjams.2021.v09i01.002

Pages: 11-13

Objective: In this study our main goal is to evaluate the clinical status of pulmonary TB patients. Method: This prospective and observational study was carried out during the period of 1st January 2010 to 31st December 2010, in the Department of Biochemistry, Sylhet M.A.G Osmani Medical College, and DOT centre, Sylhet M.A.G Osmani Medical College Hospital, Sylhet. A total of 76 subjects, both male & female 15 and 60 years of age were included in the study. Out of them 46 were smear positive newly diagnosed pulmonary tuberculosis patient (cases) and 30 were age-matched healthy subjects (control). Results: During the study, all patients were presented with weight loss followed by 95.7% had cough, fever had 84.8% cases, 34.8% had haemoptysis, 50% had chest pain. Mean (± SD) serum CRP level (mg/l) were 79.59 (± 22.71) and 7.5 (± 1.68) in cases and controls respectively at the time of diagnosis. An unpaired t-test was conducted to compare serum level of C-reactive protein between cases and controls. Serum CRP level was significantly higher in cases than controls (p <0.001).71.7% cases had unilateral opacities, 28.3% had bilateral opacities. 13% had cavity on chest radiograph. Conclusion: From our study we can conclude that, early diagnosis will prevent mortality and morbidity from this dreadful but curable disease. The available epidemiology in Bangladesh is presented in this study, but requires further study in a large scale.