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SAS Journal of Surgery | Volume-2 | Issue-04
Comparison of Complication Rates in Hip Fractures with or without Pre-existing Anticoagulation
Florian M. Kovar, Denis Holzapfel, Manuela Jaindl, Gerhard Oberleitner, Oswald F. Wagner, Georg Endler
Published: Aug. 30, 2016 |
129
107
DOI: 10.36347/sasjs
Pages: 170-177
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Abstract
According to current guidelines surgical treatment of hip fractures has to be initiated within 48h. This often
poses a challenge, as the main focus group are elderly patients with numerous comorbities and frequently medical
anticoagulation. The aim of this study was to assess the complication rate in hip fractures, anticoagulated with
phenprocumon in comparison to patients without anticoagulation. A total of 534 consecutive patients, treated in 2011,
with diagnosed hip fractures were studied with 74% being female. Age distribution was 79.9 ± 12.6, range (24.7 to
104.9). In addition to medical anticoagulation, we evaluated the time to surgery, length of stay, several blood values over
multiple time points and the mobilization as well as systemic and local complications. Out of 534 patients included in the
study, 210 (39.3%) were on medical anticoagulation. Patients who received phenprocumon reversal with vitamin K, had
the longest time to surgery (3.7 days) as well as the longest length of stay (19.5 days) while patients who received
phenprocumon reversal with human prothrombin complex (PPSBP) had the shortest time to surgery (0.1) and the shortest
length of stay (11.3 days).