DOI: 10.36347/sjams.2021.v09i01.022

Pages: 109-112

Background: Cholelithiasis is a common disease and notable advances have been made in studying the possible causes and mechanisms involved. It is not only important to study the prevalence of gallstone disease regionally, but also to explore the demographic and biological markers related to the development of gallstone disease, so that appropriate preventive measures may be undertaken. Many previous studies have shown a positive correlation between altered lipid profile and formation of gallstones. Objective: This study is to compare the serum lipid abnormalities in cholelithiasis patients. Method: This cross-sectional analytical study was carried out at Cox’s Bazar Medical College and Hospital, Cox’s Bazar, Bangladesh. Where data were collected from July 2019 to June 2020.A total of 76 who underwent cholecystectomy for gallstone disease considered for the study population. Sample were collected through purposive sampling as per inclusion criteria. Results: During the study, most of the patients belong to 36-56 years age group 47.4% and 80.3% were female. In female most patients TC were normal, 93.44% followed by 40.99% had TG in borderline, 61.94% had below normal level of LDL. Where as in male group 86.6% cases TC were in normal level followed by 26.67%cases had borderline level of TG and 60% had below normal level of LDL. There is no significant association of lipid profile level with gender. One the basis of Pearson correlation TG was positively correlated with TC, LDL and HDL, where coefficient was .474,.148.110. Similarly, the profile of LDL and HDL were negatively correlated with each other. We also found that, age was significantly and positively correlated with TC, TG and HDL and negatively correlated with LDL. Conclusion: From our result we can conclude that, female was high risk of gallstone formation and in both male and female group more 50% cases had abnormal LDL level. Further studies are needed for better outcome.