DOI: 10.36347/sjmcr.2021.v09i01.015

Pages: 55-60

Introduction: Biological wound healing consists of a cascade of cellular and molecular events. Healing processes can be influenced by a variety of factors, both local and systemic. Cutaneous and oral wounds can be either accidental or surgical. Biochemical components contained in animal or plant origin substances may promote the repair of the integrity of injured tissues by supporting blood clot formation, stimulating neo-angiogenesis, protecting the wound from infection, and inducing connective tissue formation. Topical gel applications based on mucus secreted by various snail species, alone or combined with other therapeutic options, may accelerate tissue repair and promote tissue normalization after surgical incisions, traumatic wounds, periodontal and peri-implant injuries, and infections. Materials and Methods: A literature search of the electronic databases PubMed and Google Scholar was conducted to identify which scientific articles reported the clinical use of snail slime gels as bio-stimulants in adjuvant tissue repair processes. Specifically, our focus was to identify whether clinical cases and scientific papers proposed Gelenzyme® as an adjuvant in oral wound or injury healing processes as we did in our clinical practice. Results and Discussion: Three papers and/or academic posters presenting clinical cases were identified. Besides, we decided to report our own clinical case of a patient who presented with a mechanical complication of a single implant-supported prosthetic crown. Crown fracture, detachment from the abutment and exposure of the emergent abutment in the oral cavity resulted in the adjacent lingual border erosion. The traumatic lingual injury was treated with Gelenzyme® Clinical healing appeared more rapid and rather successful with reduced local symptomatology and the absence of adverse reactions. The number and diffusion of reported clinical cases using Gelenzyme® are still limited. Conclusion: Pharmacological properties such as ...........