DOI: 10.36347/sasjs.2021.v07i02.004

Pages: 44-48

Aim: To determine the factors associated with para-central defect for primary open angle glaucoma in a Singaporean Chinese population. Methods: In a retrospective case series of Singaporean Chinese primary Open Angle Glaucoma (POAG) cohort, we analyzed the pattern of visual field defect at the first time of presentation. Diagnosis was categorized as normal tension glaucoma (NTG) if untreated presenting diurnal intraocular pressure (IOP) was ≤21 mm Hg and high tension glaucoma (HTG) if IOP was>21 mm Hg. Para central defect was defined as glaucomatous defect (p<0.5%) within 10 of fixation in pattern deviation plot and all other glaucomatous defects were grouped as non-para central defects. Para central defect (PCD)was considered the dependent variable with age, gender, logmar visual acuity (Log VA), IOP, central corneal thickness (CCT), vertical cup disc ratio(VCDR), mean deviation (MD) value, diagnosis and co-morbid conditions (hypertension, diabetes, asthma, ischemic heart disease) at presentation were considered as independent variables for multivariate regression analysis. Results: Of the 887eyes of 887 POAG patients included, 146 (16.45%) had PCD at presentation. Mean age was 62.37 (+9.9) years, males were 67.4%, 673(75.8 %) had HTG and 214(24.1%) had NTG.PCD was significantly associated with lower presenting IOP (B= -0.051, p=0.002), NTG (B = -0.672, p=0.001) and lower MD values (B = 0.077, p<0.001). Conclusion: Para-central visual field defects were associated with NTG, lower presenting IOP and less severe visual field defects at initial presentation.