DOI: 10.36347/sasjm.2016.v02i01.002

Pages: Page: 5-9

Abstract: Huntington’s disease (HD) is a autosomal inherited progressive neurodegenerative disorder that diagnosed with major clinical features having uncontrolled body movements, emotional distress and loss of cognition. Huntington disease tends to progress with the time more quickly than the adult-onset form and affected individuals with worsen neurodegenerative clinical features. The dysfunction and eventual neuronal damage is diagnosed in certain areas of the brain such as cerebral cortex and striatal part of basal ganglia in HD patients. This disease is non-curable and does not have any effective and definite treatment or medication. The preventive measures and treatment used for HD are quite helpful to manage the symptoms of Huntington's disease. But these cannot prevent the physical, mental and behavioral decline associated with its ill and worsen effects in HD patients. It is very important to know the genetic history of patients at right time with available genetic counseling and molecular assay methods to diagnose the existing symptoms during onset of this disease. Hence, it can be treated and managed well at right time in HD patients with effective neuroprotective and suggestive clinical solutions with palliative care must be used to control the clinical and genetic burden in affected population of any country.