DOI: 10.36347/sasjm.2016.v02i01.003

Pages: Page: 10-11

Abstract: It is estimated that 1-4 out of every 100 cases of acute pancreatitis are precipitated by hypertriglyceridemia. Insulin, heparin and plasmapheresis are amongst a few modalities utilized in management of these patients. Limiting dangerous complications and extended length of hospital stay in patients with hypertriglyceridemia induced pancreatitis is an important endeavor with a dearth of data for guideline directed therapy. We present the case of a patient without a history of diabetes mellitus that presented with hypertriglyceridemia induced pancreatitis and was treated with continuous insulin infusion at a rate of 0.1 units/kg/hour, which is higher than the previously reported insulin infusion dose of 0.05 – 2 units/kg/day. In doing so we were able to safely and efficiently reduce the patient’s triglyceride level as well symptomology in less than 48 hours and show the potential of using this method in future patients. Further studies with increased number of subjects may further verify this higher dose of insulin as effective for treatment of HTG-induced pancreatitis.