DOI: 10.36347/sjams.2021.v09i03.026

Pages: 428-432

Hyperparathyroidism is a disease characterized by excessive secretion of parathyroid hormone, the hormone responsible for calcium and phosphate homeostasis in the body. It can be of three types: primary, secondary, or tertiary. Secondary and tertiary hyperparathyroidism is a frequent complication of chronic kidney disease (CKD). The brown tumor is an unusual presentation of fibrous osteitis that represents a serious complication of renal osteodystrophy, affecting predominantly the hands, feet, skull, and facial bones. Case report: The aim of this paper is to describe the case of a 39-year-old female patient, with chronic kidney disease who has been on dialysis for 11 years and developed severe tertiary hyper- parathyroidism, brown tumor of the face, that has caused constant pain, malocclusion and deformation facial, and diffuse osteopathy with bone squelet deformation and thoracic deformation, in whom the treatment consisted of parathyroidectomy. Despite the normalization of serum parathyroid hormone and alkaline phosphates, tumor regression was slow and patient’s important functional and esthetic deficits persisted. The prevention and treatment of secondary and tertiary hyperparathyroidism remains a permanent challenge for nephrologist. The brown tumor of the face is a severe complication of early hyperparathyroidism hence the interest of screening and treating patients with especially chronic hemodialys.