DOI: 10.36347/sasjm.2021.v07i03.004

Pages: 79-84

Introduction: For men prostate cancer is most commonly occurring cancer and it is responsible for fifth leading cause of death in whole world (3.8% of all deaths caused by cancer in men in 2018). For developed country prevalence rate is much higher however there are reports which revealed higher incidence of positive bone scan with low PSA in mass population screening in Asians as compared with western data. Aim of the Study: To identify correlation and incidence of bone metastases in prostate cancer patient with low Gleason scores (GS) and prostate specific antigen (PSA) levels. Material & Methods: This was a retrospective study of prostate cancer patients referring to Institute of Nuclear Medicine and Allied Sciences, Khulna, Bangladesh for bone scan form January 2020 to December 2020. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) version 22.0. Results: There were 58 patients with prostate cancer in January 2020 to December 2020 and 45 patients with the complete data. The patients were of age 53–89 years, with mean age of 68.41 ± 7.5 years. The incidence of osseous metastases proven by bone scan was found to be 1 out of 5(25.00%) for PSA level>20 ng/ml, (20-60 ng/ml); 9 out of 17 (52.94%) for PSA level (60–100) ng/ml; 10 out of 12(83.33%) and 100% for PSA >100 ng/ml. All patients (n = 11) with PSA >100ng/ml was having BM. Conclusion: There was high incidence of BM in diagnosed PC in our study (68.89%) compared to other studies; PSA and GS positively related to the incidence of BM; and there were still small number of patients had BM with low GS and PSA.