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SAS Journal of Medicine | Volume-7 | Issue-03
Correlation of Prostate Specific Antigen, Gleason Score and Bone Metastases in Bone Scan in Prostate Cancer Patient
Das J, Paul AK, Haque N, Dan KK, Saha S, Khan TI, Masum TR,Hossain N, Zareen N
Published: March 23, 2021 | 151 228
DOI: 10.36347/sasjm.2021.v07i03.005
Pages: 85-89
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Abstract
Introduction: Diabetes mellitus (DM) is a result of heterogeneous metabolic disorders, causes hyperglycemia due to deficiency in secretion and/or insulin action. The present retrospective cross-sectional study was done among 78 T2DM patients. Serum 25-hydroxyvitamin D [25(OH)D] levels reflect body stores of vitamin D which was measured in all and classified as normal (≥30ng/mL), insufficient (>20 to 29.9ng/mL), and deficient (≤20ng/mL). The mean serum 25(OH) D level was 27.91±2.58ng/mL (mean±SD). Aim of the Study: Aim of the study was to find out the vitamin D status in type 2 diabetes mellitus patients. Methods: This retrospective cross-sectional study was conducted in SMC Niltara Clinic, Dhaka, Bangladesh during the period from January 2020 to December 2020. All the results were statistically analysed by were taken by SPSS-20 version and MS-Excel-16. Result: In total 78 patients divide into two groups. In Vitamin-D status was 24(41.38%) found normal in male and 8(40.00%) in female; insufficient found 22(37.93%) in male and 11(55.00%) in female; deficient found 12(20.69%) in male and 1(5.00%) in female. There was no statistical difference of 25(OH)D level between males and females (26.79±2.1 vs. 31.09±8.2ng/mL, mean±SEM; p=0.470); among smokers, non-smokers and ex-smokers (26.86±4.31, 27.10±2.49 and 42.62±1.71ng/mL respectively, mean±SEM; p=0.363); among normal weight, overweight and obese (30.61±6.16, 35.61±9.52 and 24.27±1.71ng/mL respectively, mean±SEM; p=0.191); and among normotensive, borderline hypertensive and hypertensive (25.29±2.46, 32.57±5.32 and 20.84±3.66ng/mL respectively, mean±SEM; p=0.277) patients. 25(OH) D level showed significant negative correlation with body mass index (r= -0.391, p=0.017) and positive correlation (r=0.334, p=0.044) with fasting plasma glucose in male subjects. Conclusion: A large portion of Type-2 diabetes mellitus (DM) subjects in Bangladesh has subnormal vitamin D as revealed by our study. Vitamin D level had a significant..