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SAS Journal of Surgery | Volume-3 | Issue-02
The Effect of the Combination of Allium Extract, Heparin and Allantoin Gel in the Overall Appearance of Post Thyroidectomy Scar
Mebin Mathew, Premkumar A
Published: Feb. 28, 2017 | 138 158
DOI: 10.36347/sasjs
Pages: 57-60
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Abstract
Scar is a part of natural healing process. Lot of treatment options are available today to improve the cosmesis of the scars which includes topical agents like retinoic acids, intralesional injections like triamcinolone, surgical excision ,laser treatment etc Here the study is regarding the use of the combination of three molecules allantoin, heparin and allium and evaluates the efficacy of the combination rather than individual components. 20 patients were included in the treatment group and 20 were included in the control group who did not receive any treatment. Three follow ups done in 4th week, 6th week and 10th week. Patient’s feedback scores were recorded using a 4 point ordinal scale. The enquiries were made on the overall appearance including the texture, and softness of the scar. The data collected is analyzed using appropriate statistical methods. The mean score of the treatment group after 4 weeks is 1.6 and that of control is 0.9.There is significant difference between the scores with a p value of 0.006. The score is improved in both the groups after 6 weeks of starting the treatment. After 10 weeks of the treatment the same trend continued and the score become 2.45 in the treatment group and 1.45 in the control group which again showed significant improvement. The combination of the three drugs, Allium cepa extract, Heparin and Allantoin has got significant effect in the improvement of overall appearance of post-surgical scar with three times application daily over a period of 9 weeks.