DOI: 10.36347/sjams.2021.v09i04.011

Pages: 546-548

Aim: The aim of the present study is to study the efficacy of sublingual administration of misoprostol in the management of missed abortion. Materials and Methods: It was a randomized controlled study conducted in Department of Obstetrics & Gynaecology, SMS Medical College, Jaipur on 120 patients diagnosed as missed abortion by ultrasonographic examination. Cases were given- tab misoprostol 400 g sublingually every 3 hrs for maximum of 4 doses. Patients were observed for the induction-abortion interval, amount of vaginal bleeding, number of doses required, presence of RPOC, need for evacuation and side-effects. Result: During the follow-up of our cases we found that sublingual route is effective in the management of missed abortion. 78.33%women had complete abortion and do not require evacuation .Mean induction abortion interval was 11.01 hours. Mean dose required was1084mg, these women experienced side effects including nausea and vomiting (20%) and diarrhoea (16.67%), fever (15%). Conclusion: Sublingual administration of misoprostol is effective in missed abortion management.