DOI: 10.36347/sjmcr.2021.v09i04.008

Pages: 340-341

About 30% of the patients with Myasthenia Gravis (MG) develop respiratory muscle weakness. Exacerbation of myasthenia gravis can cause severe respiratory muscle weakness leading to respiratory failure requiring mechanical ventilation. Sleep disorder breathing is seen in about 40 to 60% of patients with myasthenia gravis. Continuous positive airway pressure (CPAP) will not only reverse sleep disordered breathing but also weakness and fatigability during daytime called as “proximal weakness”. Here we report a case of 51 years old male myasthenia gravis patient diagnosed with obstructive sleep apnea (OSA). After initiation of CPAP therapy patients OSA symptoms improved along with his paradoxical weakness.