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Scholars Journal of Applied Medical Sciences | Volume-9 | Issue-05
Biochemical Parameters in Detecting Malnutrition and Inflammatory Markers in CAPD Patients
Mekhola MH, Chowdhury MAA, Alam KS, Alam MB, Akbar AAG, Saha S, Hossain MS, Rahman MH, Sultana M, Rahman MR, Tahsin S, Shahriar S, Sukur MA
Published: May 24, 2021 | 144 120
DOI: 10.36347/sjams.2021.v09i05.021
Pages: 736-740
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Abstract
Background: The nutritional status of dialysis patients can be determined by biochemical Parameters, anthropometry, protein catabolic rate, and body composition methods. Over the past decade, various nutritional parameters have emerged. Objective: The aim of the study was evaluation of biochemical parameters in detecting Malnutrition and Inflammatory Markers in CAPD Patients. Methods: The cross-sectional study was conducted in the Department of Nephrology of National Institute of Kidney Diseases and Urology, Dhaka, Bangladesh to Detect Malnutrition and Inflammatory Markers in CAPD Patients. They were identified based on hospital registry and Peritoneal Dialysis service provider. 69 cases were randomly selected for the study. Clinical examination and evaluation were done from July 2018 to June 2019. Other necessary investigations were done if clinically indicated. Statistical analysis of the results was obtained by using window-based computer software devised with Statistical Packages for Social Sciences (SPSS-22). Results: Out of 69 patients 39 were male (56.5%) and 30 were female (43.5%). 49.3% were diabetic, 30.4% had GN, 15.2% had HTN & 2.9% had OU & 1.4% had PKD. Mean Hb of Patients were 9.48 ± 1.77 (g/dl). Mean S Creatinine was 9.32 ± 3.94 (mg/dl). Mean CRP was 23.73 ± 26.67. Mean Albumin was 3.11 ± 0.60 (mg/dl). Mean Prealbumin was 0.30 ± 0.11 (ng/ml). Mean TIBC was 165.8 ± 59.5. S-albumin & S-prealbumin was significantly lower in patients with higher MIS-score (>5). Conclusion: Biochemical parameters and inflammatory markers significantly correlate with malnutrition among patients on CAPD.