DOI: 10.36347/sjams.2021.v09i06.001

Pages: 751-759

Micro-organisms have always been a part of the ecosystem. In fact, they play a major role in balancing metabolism as they colonize the system. In the past two decades, studies about the human micro biome has been elevating and still continuing as it is perceived as a possible threat to health status or also could be promising and hope filling in novel therapeutics in the mere future. Despite many on-going debates about the relationship of gut bacteria to the physiopathology of cardiovascular diseases, it has been simultaneously established through ample amount of reports and studies conducted both in vivo and in vitro. In this review, we will be stressing on several studies emphasizing on the gut micro biome, their role in influencing the physiopathology of cardiovascular diseases while also reflecting CVD as a global health burden, factors affecting the differences in gut microbiota, gut dysbiosis and its effects on the hosts’ metabolism, the intervention of probiotics in balancing gut dysbiosis, bacteriotherapy and the possible hypothesis of SCFAs and TMAOs to be explored on manipulating the gut microbiota in preventing blood pressure, obesity and hypertension which are major risk factors for cardiovascular diseases.