DOI: 10.36347/sjams.2021.v09i06.021

Pages: 929-934

Background: Gallstones are the most common cause of emergency hospital admission for people with abdominal pain worldwide. In most of cases they don't cause any symptoms and no need to be treated. Material and methods: A prospective study conducted on 100 patients involving all diagnosed patients of cholelithiasis admitted and supposed to undergo Laparoscopic Cholecystectomy. The first fifty patients undergoing elective Laparoscopic Cholecystectomy will be given injection Ceftriaxone 1.5 gm i.v. after the test dose outside the operation theater in the wards and the antibiotics were continued for 2 days. The next fifty patients were given a single dose of injection Ceftriaxone 1.5 gm i.v. after the test dose just before the induction of anaesthesia. Results: Majority of the cases belongs to 35 patients were in 18-30 years age group, 86 (86%) were females. Our study shows that incidence of Cholelithiasis is more among females which is consistent with general population. Out of the 100 cases of elective Laparoscopic Cholecystectomy, drain were placed in 45 (45%) patients, and no drain required in 55 (55%) of patients. Out of 50 patients of single dose antimicrobial group 32 (64%) developed post-operative fever, 3 patients (6%) had post-operative raised WBC count and 3 patients (6%) had post-operative surgical site infection. Out of 50 patients of multidose antimicrobial group 31 (62%) had post-operative fever, 2 patients (4%) had post-operative raised WBC count and 2 patients (4%) had post-surgical site infection. Conclusion: There is no statistical difference between single dose and multi dose antimicrobial treatment in terms of surgical site infections and post-operative hospital stay.