DOI: 10.36347/sjmcr.2021.v09i07.005

Pages: 707-710

Introduction: Balo's concentric sclerosis (BCS) is a particular and rare demyelinating disease of the white matter of the brain that was first described by J. Balo in 1928 and considered as a rare variant of multiple sclerosis. The clinical manifestations usually consist of aphasia, behavioral disturbances, and seizures. This term results from a pattern of concentric aspect of the lesions with alternating areas of demyelination and areas of normal myelin in various parts of the brain and spinal cord. BCS was described as monophasic, progressive, and treated as a disease with a fulminant course. Case report: We report a case of 38 years old woman who developed slurring of speech with mild swallowing disorders for solid foods accompanied by vertigo. Her MRI showed “onion peel-like” demyelinating lesions over the subcortical areas of the left parietal lobe. Treatment given to the Patient was IV methylprednisolone followed by oral corticosteroids, with a favorable outcome without clinical recurrence after two years of follow-up. Conclusion: BCS is a rare disease with an unpredictable course, the pathognomonic brain MRI features help to secure the diagnosis. The clinical case described is interesting because of the rarity of this entity.