DOI: 10.36347/sasjs.2021.v07i07.005

Pages: 378-383

Background: Surgical site infection or SSI is an infection that occurs after surgery in the part of the body where the surgery took place. To treat surgical site infections, several antimicrobials are used for this treatment. Due to higher risk of death, patients with SSIs are more likely to require readmission to hospital or intensive care unit (ICU). So, the sensitivity pattern of different causative organisms involved in SSI may support the surgeons as a treatment manual in treating SSI patients. Aim of the study: The aim of this study was to identify the drug sensitivity pattern of different causative organisms involved in the process of surgical site infection. Methods: This cross-sectional study was conducted in the Department of Surgery, in A Tertiary Care Hospital, Dhaka, Bangladesh during the period from August 2017 to July 2018. A total of 160 admitted patients who undergone the surgical procedure at the mentioned hospital were enrolled as the study population. Before using any antimicrobial blood culture as well a swab from wound culture was sent for confirmation of infection and culture sensitivity. All data were processed, analyzed, and disseminated by MS Office and SPSS version 22.0 as per need. Results: The most common organism involved in SSI was S. aureas (42.4%), followed in decreasing order by E. coli (27.3%), P. aeruginosa (12.1%), bacteroids (12.1%), and Klebsiella spp. (6.1%). In analyzing the drug sensitivity status, we found Meropenem as the most sensitive drug followed by Ceftriaxone according to coverage and efficacy. As per only coverage, Ceftriaxone showed better efficacy than that of other drugs. On the other hand, Gentamycin showed cent percent sensitivity for gram-negative organisms only. Conclusion: Considering the findings of this study we can conclude that Meropenem and Ceftriaxone may be considered as the most effective antibiotic in treating patients with surgical site infection. In such cases, applying very traditional or .......