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Scholars Journal of Applied Medical Sciences | Volume-9 | Issue-07
The Correlation between Serum Ascites Albumin Gradient and Oesophageal Varices in Chronic Liver Disease
Dr. Forhad Hossain Md. Shahed, Professor Mamun Al Mahtab, Professor Nooruddin Ahmed, Professor Mobin Khan, Dr. Noor Jahan Alam Chowdhury
Published: July 30, 2021 | 143 111
DOI: 10.36347/sjams.2021.v09i07.020
Pages: 1235-1240
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Abstract
Background: Oesophageal varices are abnormally enlarged veins in the tube that connect the throat and esophagus. Such condition occurs most often in people with serious liver diseases. On the other hand, chronic liver disease denotes the disease of the liver which lasts over a period of months or more. The serum ascites albumin gradient (SAAG) is a formula that is used to assist in determining the etiology of ascites. We don’t have any research-based information regarding the correlation between serum ascites albumin gradient and Oesophageal varices in chronic liver disease. Aim of the study: The aim of this study was to assess the correlation between serum ascites albumin gradient and Oesophageal varices in chronic liver disease. Methods: This prospective observational study was conducted in the Department of Hepatology, BSMMU, Dhaka, Bangladesh during the period from January 2005 to December 2005. In total 50 patients with cirrhosis with ascites with high SAAG values (>1.1 gm/dl) were included as the study people. The age of the patients was 15 to 70 years. Both males and females were included in the study. All data were entered into a personal computer, thoroughly checked for any possible error, and then processed and analyzed by the SPSS program. The significance of the test was tested by the chi-square test. P-value of <0.05 was taken as statistically significant. Correlation analysis was done by the Pearson correlation test. Results: In this study, in the SAAG group 1.10-1.49 gm/dl, there were 15 patients, 8 patients (53.28%) of them had small varices, 4 patients (26.64%) had medium-sized varices and 2 patients (13.32%) had large-sized varices. In the SAAG group 1,50-1.99 gm/dl, there were 9 patients, 1 patient (11.11%) of them had small sized varices, 6 patients (66.66%) had medium sized varices and 2 patients (22.22%) had large-sized varices. In SAAG group >2 gm/dl, there were 26 patients. Nine (9) patients (34.2%) of them had small-sized varices, ..........