DOI: 10.21276/sasjs.2017.3.12.1

Pages: 291-306

Appendicular Perforation rates range from 4% to 45%, death rate range from 0.17% to 7.5% and in patients with acute appendicitis may cause a variety of potentially life threatening complications and is responsible for a considerable amount of morbidity. In this study we found that hyperbilirubinemia has a clear edge over the others when used to diagnose established perforation (diagnostic accuracy of 92% and PPV of 66.67%). In this scenario, leukocytosis has high diagnostic accuracy (76.67%) but low positive predictive value (25.71%). When used to diagnose cases with established perforation plus impending perforation i.e., gangrene the positive predictive value of CRP-test shoots up (57.14%). But it still remains lower than that of leukocytosis (77.14%) and hyperbilirubinemia (66.67%). However, its diagnostic accuracy (78%) surpasses that of bilirubin levels