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Scholars Academic Journal of Pharmacy | Volume-8 | Issue-12
Polymeric Micelles as Novel Nanocarriers for Improving Drug Solubility, Absorption, and Targeting Efficiency: A Review Article
Marianne Joseph Naguib
Published: Dec. 30, 2019 | 119 80
DOI: 10.36347/sajp.2019.v08i12.007
Pages: 552-559
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Abstract
A major problem for the formulation of safe, effective, and economic dosage forms is the formulation of molecules that have very low water solubility. Incomplete drug dissolution would at the end lead to decreased drug absorption that will finally affect drug bioavailability. Another aspect is the increasing need to target drug release. Targeted drug release, increases drug amount at the site of action improving drug efficacy and decreasing its side effects, this review article aims to focus on the interesting properties of polymeric micelles ranging from drug solubulilization to the capability of achieving drug targeting.