DOI: 10.36347/sjams.2021.v09i09.023

Pages: 1431-1436

Introduction: Elevated serum lipid levels are associated with an increased risk of retinal hard exudate in persons with diabetic retinopathy. Although retinal hard exudates usually accompany diabetic macular edema, increasing amounts of exudate appear to be independently associated with an increased risk of visual impairment. Objective: To evaluate the role of lipid profile and glycosylated haemoglobin on fundus changes in diabetic patients. Materials and methods: This is a cross sectional study conducted in Department of Ophthalmology Out patients and in patients of tertiary care teaching hospital. Patients were enrolled for the study after obtaining written informed consent. Total 214 patients were screened in this study. Collected data was analysed by both descriptive and inferential methods. Result: Majority of patients were in age group of 40-60 years with mean age 54.47 ± 12.24 years. Statistically significant correlation was found with increasing age and incidence of diabetic retinopathy (p=0.016). The prevalence of DR shown male predominance with male to female ratio was 2.6:1. Significant correlation was observed between triglyceride (p=0.007), total cholesterol(p=0.002) and LDL(p=0.149) levels with diabetic retinopathy. A positive correlation was observed between glycosylated haemoglobin (p<0.001) and severity of diabetic retinopathy. Conclusion: In our study a statistically significant correlation was obtained between severity of diabetic retinopathy with serum total cholesterol, triglycerides and LDL and glycosylated haemoglobin.