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SAS Journal of Medicine | Volume-2 | Issue-02
Study of cervical cytology in users of progestagen-only contraceptives
Tawfik Abdel Salam Tawfik, Mervat Aly El-Din Hamza, Ziad Sami Abou-Zeid, Hebatallah Said Abd El-Fattah Salem
Published: April 30, 2016 |
98
82
DOI: 10.36347/sasjm.2016.v02i02.004
Pages: Page: 40-43
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Abstract
Early detection of cervical precancerous lesions by cervical cytologic examination has dramatically decreased
the risk of cervical malignant disease. There is always a major concern about the relationship between hormonal
contraception and cervical malignancy. The objective of this study is to define the relationship between the use of
progestagen-only contraception and the occurrence of abnormal cervical cytology. In Methods Cervical cytologic smears
were taken from 250 women attending El-Shatby family planning-clinic including 200 progestagen-only contraceptive
users as cases group and 50 non-hormonal contraceptive users as control group. In results cytologic examination revealed
epithelial cell abnormalities in 44 (22%) smears including ASCUS in 31 (15.5%), LSIL in 11 (5.5%) and HSIL in 2 (1%)
of cases. Control group showed 9 (18%) positive smears including ASCUS in 6 (12%), LSIL in 3 (6%) smears. There is
no statistically significant difference between both groups. In conclusion the Progestagen-only contraceptives are not
associated with increased risk of abnormal cytologic findings and preinvasive disease of the cervix.