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Scholars Journal of Applied Medical Sciences | Volume-9 | Issue-10
Topical Testosterone Therapy Prior to Hypospadias Repair (Our experience at Queen Rania Al-Abdullah Hospital for Children)
Bahaa Abdallah, Salim Masadeh, Amer Alibrahim, Salameh Samawi, Omar Alyabrodi, Ahmd Alremony
Published: Oct. 11, 2021 | 158 108
DOI: 10.36347/sjams.2021.v09i10.009
Pages: 1533-1536
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Abstract
Objective: As hypospadias is one of the most common congenital male anomalies, furthermore, multiple approaches and methods of treatment were mentioned over the references, we tried to put our thumbs on one of the most preoperative steps which can be missed or has multiple debates during a discussion about it. Here in our study, we focused on the rule of topical testosterone treatment on multiple patients as an advantageous step to get a higher rate of success postoperatively side by side to achieve a good penile size intraoperatively. Deep detailed analysis of side effects of topical testosterone balanced with the duration of surgery, short and long-term outcome. Methodology: The study was carried out from January 2014 to January 2019 at Queen Rania Hospital for children, Amman, Jordan. The overall number was 182 patients. We divided them into two groups: (group A) 98 boys who did not receive the hormonal treatment and (group B) were referred to the patients who underwent the topical treatment and their number was 84. The age group was between 6 months and 6 years. Testosterone gel 1% was applied as a thin layer over the ventral aspect of the penis once daily for 3 weeks before surgery. The patient’s degree of hypospadias as glandular, coronal, distal shaft, and midshaft to illustrate the benefits on each group. The local and systemic side effects of the gel were documented. Concomitantly we measure the difference in penile length, glans width along with serum testosterone level before and after applying it. After that, the mean duration of surgery was measured. The common complications of surgery were listed as fistula, glans dehiscence, meatal stenosis and the number of each complication for each group was documented and analyzed. Results: There were good results related to the mean penile length and glans width no significant change related to the serum testosterone level. No valuable change upon the duration of surgery. Local skin pigmentation with ............