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SAS Journal of Medicine | Volume-7 | Issue-10
IgE Abnormalities in Patients with Bronchial Asthma
Dr. Ganesh Chandra Haldar Saurav, Dr. Ajit Kumar Paul, Dr. Uma Dash, Dr. Abu Syed Mohammad Tareq, Dr. Makhan Lal Paul, Dr. Aparna Rahman, Dr. Md. Bashir Uddin
Published: Oct. 14, 2021 | 116 82
DOI: 10.36347/sasjm.2021.v07i10.008
Pages: 552-555
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Abstract
Introduction: Bronchial asthma is a medical condition that causes a deformity in the airway path of the lungs, causing them to swell and get narrow. The swelling produces excess mucus in the pathway, making it hard to breathe, and this results in coughing, short breath, and wheezing. This is often caused by allergic reaction to outside stimulants. The allergic reaction causes the body to produce Immunoglobin E antibodies that help the immune system fight back against allergens, but excess production of IgE can lead to severe allergic reaction and respiratory difficulties. Aim of the study: The aim of the study was to observe the IgE levels of Bronchial Asthma patients. Methods: This was a prospective cross-sectional study was conducted in the Department of Medicine, Mainamoti Medical College Hospital, Cumilla, Bangladesh during the period from January 2020 to July 2020. Fifty-three (53) patients were selected maintain inclusion criteria. Proper written consents were taken from all the participants before starting data collection. A pre-designed questionnaire was used in patent data collection. All data were processed, analyzed and disseminated by MS Office and SPSS version as per needed. Result: The present study had 53 participants in total. 45.28% of the participants were aged between 41-60 years, and 32.08% were aged between 21-40 years. 34% were male and 66% were female, and the male: female ratio was 1:1.95. 49 participants were diagnosed with bronchial asthma while 4 did not have asthma. 30.19% had mild asthma with Mean±SD IgE of 464.000±57.10, 26.42% had moderate asthma and Mean±SD IgE of 695.410±82.09, and 35.85% had severe asthma with Mean±SD IgE of 1045.320±14.16 IU/ml. Conclusion: The study found that asthma can be different according to age, and older women have a higher prevalence of asthma, compared to older male population. IgE levels of above 100 IU/ml can be abnormal, and according to WHO guidelines, IgE levels of >150 can be considered as an ......