DOI: 10.36347/sasjs.2021.v07i10.020

Pages: 617-621

Background: Acute pancreatitis remains difficult to diagnose. The disease may occur at any age, with a peak in young men and older age. It is defined as an inflammatory process of the pancreas with possible peri- pancreatic tissue & multi-organ involvement inducing multi-organ dysfunction syndrome with an increased mortality rate. Majority of patients present with a mild disease, however approximately 20% run in a severe course and require appropriate management in an intensive care unit. According to the Atlanta Classification, severe acute pancreatitis is defined as an acute pancreatitis associated with local and/or systemic complications. Acute pancreatitis remains difficult to diagnose. The disease may occur at any age, with a peak in young men and older age. Objectives: The aim of the study was to determine prognostic role of biochemical markers in severe acute pancreatitis. Methods: The Study was conducted in the department of surgery of Dhaka Medical College Hospital, Dhaka, Bangladesh to find out the common indications of prognostic role of biochemical markers in Severe Acute Pancreatitis. Fifty cases were randomly selected for the study. Clinical examination and evaluation were done from May 2017 to November 2017. Other necessary investigations were done if clinically indicated and to prepare the patient for anesthesia. Statistical analysis of the results was obtained by using window-based computer software devised with Statistical Packages for Social Sciences (SPSS-22). Results: The maximum number of patients 23(46.0%) was found in the 31-40 years of age, the next was 16(32.0%) found in 41-50 years and the lowest percentage was 11(22.0%) in the 50-60 years. The mean age of the study group was 41.86±8.27 years, minimum age 31 and maximum 58 years. Conclusions: Clinical, biochemical parameters are related to the clinical course of acute pancreatitis and they can predict its severity. However, acute pancreatitis is a very complex disease, and despite.........