DOI: 10.36347/sjmcr.2021.v09i11.010

Pages: 1080-1082

Polymicrogyria results from a disruption of the final neuronal migration process leading in small brain convolutions delimited by shallow cortical grooves. We report two cases: The first is a 23-year-old patient, from a poorly followed up pregnancy, with neonatal suffering, delay in motor and mental acquisitions, complaining of recurrent convulsive seizures not improved by medical treatment. The second case is a 39-year-old patient followed up for epileptic seizures of parietal appearance on electroencephalogram, treated by antiepileptic since the 20 years age without improvement. Brain MRI noted bilateral thickening of the cortical band in the parieto-occipital cortical areas in the first patient and in the fronto-parietal areas in the second, with numerous shallow cortical grooves, delimiting shallow convolutions, without anomalies in hippocampal formations. Polymicrogyria is a cortical malformation characterized by the presence of small convolutions with slightly pronounced cortical grooves. Epilepsy is the most common manifestation. It is diagnosed on MRI showing numerous shallow cortical cerebral furrows.