DOI: 10.36347/sjmcr.2021.v09i11.017

Pages: 1105-1108

Oculo cutaneous albinism [OCA] is a autosomal recessive disorder associated with reduction in the pigment of skin, hair and eyes with strabismus and nystagmus leading to misrouting of optic nerve fibers from eye to brain during development. Reduction in skin pigmentation leads to the increased risk of skin cancer due to photosensitivity. They can occur in isolated forms or associated with syndromes. Syndromic OCA includes oculocutaneous albinism with hermansky pudlak syndrome. Seven types of OCA [1-6] with mutation in different genes have been identified.